What is considered a normal range for serum creatinine levels in adults?

The normal range for serum creatinine levels in adults is 0.6 to 1.2 mg/dL. This range is established based on a population-based understanding of kidney function and muscle mass, as creatinine is a waste product generated from normal muscle metabolism. The kidneys are responsible for filtering creatinine from the bloodstream, and therefore, serum creatinine levels provide an indication of kidney function.

Values below this range may suggest low muscle mass or some other underlying condition, while values above this range could indicate impaired kidney function, necessitating further investigation. Furthermore, serum creatinine levels can vary based on factors such as age, sex, and diet, which is why the reference range incorporates variability but still centers around the 0.6 to 1.2 mg/dL bracket for most adults. Understanding this normal range is critical for assessing renal health and guiding patient management in nephrology.